South African Women’s Wellness Webinar 2024
Making a Difference by Prioritising Women's Wellness On the 27th of August 2024, in celebration of Women’s Month in South Africa, we hosted an inspiring internal webinar on Women’s Wellness, moderated by our very own THINKer Michaela Higgins Sørensen. The session explored what wellness truly means for women, acknowledging the many layers and challenges involved. We were fortunate to hear from three insightful in-house speakers: Camilla Lund, Dr Suzanne Staples, [...]
Fostering a Culture of Health and Safety
At THINK, we are deeply committed to fostering a culture of health and safety. To ensure a safe workplace, we have implemented specialised training programmes, including Safety, Health, and Environment Representative (SHE Rep), First Aider, and Firefighter courses. These programmes equip our THINKers to handle safety and emergencies effectively. We are particularly impressed by the dedication of our THINKers who volunteered to become Health and Safety Ambassadors, going above and [...]
Raising Awareness for Mental Illness
Mental Illness Awareness Month: Collaborative Event at Deneysville Clinic In recognition of Mental Illness Awareness Month this July, the Department of Health (DOH), in partnership with the Fezile Dabi District Mental Health Unit and THINK, organised a significant collaborative event at the Deneysville Clinic in the Free State, South Africa. The initiative aimed to raise awareness about mental wellness, save lives, and break the stigma associated with mental illness. [...]
Cultivating Community Strength
Six Stories of Unity and Action 1. Transforming Health in Phaphazela Village, Vhembe District, Limpopo In June, Phaphazela Village in Vhembe, Limpopo, hosted a dynamic TB Awareness Campaign, bringing together THINK South Africa, Wits RHI, the Department of Health, and other key partners. Supported by the Soul City Institute, this event provided essential health services such as HIV testing and TB screening. Collaborative efforts with organisations like CHoiCe Trust [...]
Unpacking Menstrual Health
We recently had a fantastic webinar about menstrual hygiene, hosted by our very own Camilla Lund, and wow, did it spark some eye-opening conversations! Let's hear what Camilla has to say... We really got into the nitty-gritty of what happens during our cycles and how it can throw us for a loop, both physically and mentally, but also how we can harness these loops for our benefits! Here's the lowdown [...]
Diaries of a THINK Intern
Making a Difference Through Ethical Communications At university, for years, I had been learning the importance of using communication to make an ethically driven impact. However, it is one thing to read and learn about this, in comparison to actually doing it. At THINK, in the span of weeks of starting my internship, I learned the reality of it. From the get-go, I had been taught the real-life possibilities and [...]
A Collage of Community Impact
In the last quarter, THINK South Africa showcased their steadfast commitment to community health and empowerment through strategic partnerships and impactful interventions, paving the way for transformative changes in public health. These initiatives were part of a broader series of events held across the country. Mpola Clinic TB Awareness Event: April 7At Mpola Clinic in the eThekwini District, THINK hosted a TB awareness event focusing on research participation. Nearly 100 [...]
Innovative TB Detection and Care
THINK South Africa, generously supported by USAID, played a pivotal role at the 8th South African TB Conference held from June 4-7 in Durban. Themed "Accelerating Progress to End TB," the conference convened global experts to address the urgent challenge of combating TB, which affects millions in South Africa. Our goals at the conference were clear: to illuminate innovative solutions, share best practices, and forge collaborations with global experts. Our mission [...]
Brand Bootcamp Done & Dusted
The fabulous Mighty Ally 40-Day Brand Bootcamp is complete, and we are so ready to implement new communication and marketing strategies!Effective communication often falls by the wayside in non-profit organisations, where resources are focused on core missions such as groundbreaking research. At THINK we have recognised the crucial role of communication in amplifying our impact. To this end, we embarked on the Mighty Ally 40-Day Brand Bootcamp in November 2023.We [...]
Knowledge is Power
THINK Ambition Statement Elucidated THINK and Deloitte have joined forces to accelerate progress and implement forward-thinking strategies through the decision optimiser process. This process will enhance resilience and readiness for the future in all THINK initiatives. This exciting partnership will boost THINK's efficiencies by optimising decision-making processes and maintaining a leading edge in the NGO sector. THINK's Ambition "Our ambition is to create a future where no life is [...]
Thank You, Fellow THINKers
Meet our beautiful Ziningi Ntsele, who honours THINK values daily and appreciates, respects and cares for her colleagues. Hi everyone, my name is Ningi! When I came to join THINK at Hilton in 2019, I was so excited to become part of this organisation. My new colleagues, especially Ayanda Magoso and Deborah Nzama, really made me feel at home from day one. It was so wonderful to be part of [...]
Copenhagen’s Summer Interns
Let’s learn a bit more about our two new summer interns at the THINK Denmark office! Hi! My name is Mikkel Schlosser, and I'm excited to be working as the new HR intern at THINK for the summer! I've got a Bachelor's degree in International Business in Asia, and a Master's in Diversity & Change Management, both from CBS. I've been to Japan numerous times and have spent about a [...]
Let’s Ignite Self-Awareness!
Why is self-awareness so important in the workplace? Let's take a closer look! Self-awareness is the ability to recognise and understand your own thoughts, feelings, and emotions. It’s a key part of emotional intelligence, because knowing yourself and how you impact others will help you maintain strong relationships, build trust, and improve communication. According to the insightful blog cloverleaf.me, self-awareness is no longer just about individual well-being. There is [...]
Upcoming TB Conference: Speakers
The 8th South African TB Conference is scheduled to take place from June 3-7 at the International Convention Centre (ICC) in Durban. This conference provides an essential forum for discussing tuberculosis (TB) control and related challenges. THINK will be represented by Masingita Lambane, who heads the Strategic Partnerships and Community Systems. Masingita will be present in various parallel discussions and cover the following topics: Unlocking Health Beyond TB: The [...]
Accelerate 2 TB Technical Lead: Dr Thato Mosidi
In this Q&A session we find out more about Dr Mosidi and her role in the USAID Accelerate 2 project. Q: Please tell us briefly what this big, exciting project entails. A: ACCELERATE 2 embodies a beacon of hope and vitality for those it serves. While its primary focus lies in TB control, the project extends its reach to fortifying the systems and processes within our healthcare sector, particularly [...]
The Accelerate 2 Project Forges Ahead
The USAID-funded Accelerate 2 TB project team converged in Centurion recently, for their inaugural quarterly review meeting, to get an overview of the Accelerate 2 project – discussing the work plan, expectations, organogram, and the project’s technical approach. In attendance were THINKers from our National Office, the provinces of Free State and Limpopo, and the districts of Vhembe, Sekhukhune, Fezile Dabi, and Mangaung. The team convened to assess progress, [...]
Successful SASUF Workshops
From coffee-fuelled conversations about AI advancing healthcare to networking and breaking barriers across north-south divides, the THINK x SASUF Satellite Events, held in Copenhagen, were a journey of insights and connections! THINK Network hosted two workshops, as part of the South Africa - Sweden University Forum (SASUF) Satellite Events 2024. The first workshop was about Sustainable Global Health Care and the Role of AI in Bridging North-South Divides, and [...]
Updates from the Hillcrest Clinical Trial Unit
ChiliPref SF Study Site Visit The Hillcrest Clinical Trial Unit (HCTU) conducted a site initiation visit for the ChilPref SF study with team members from the Desmond Tutu TB Centre. The visit occurred from April 24 to 26. This particular study is one of multiple studies within the BENEFIT Kids programme funded by @Unitaid, and it focuses on identifying the most palatable formulations for crucial medicines used for the [...]
Accelerate 2 Deputy Chief of Party: Dr Chipo Mutambo
In this Q&A session, we find out more about Dr Mutambo and her role in the USAID Accelerate 2 project. Q: Please tell us briefly what this big, exciting project entails. A: The Accelerate 2 project is an initiative funded by USAID aimed at supporting South Africa's mission to eliminate tuberculosis (TB) in 7 high burden districts. Through targeted interventions focused on early detection, appropriate treatment, and prevention, particularly [...]
International Nurses Day 2024: Celebrating Our Nurses
By Michaela Higgins Sørensen and Aria Ziyuan Zhou In the spirit of International Nurses Day, it is crucial to reflect on the invaluable contributions of nurses to healthcare as well as their pivotal role in shaping the future of care. This year's theme, ‘Our Nurses. Our Future. The Economic Power of Care,’ highlights the significant impact that nurses have on the health and the economic stability of communities worldwide. To [...]
Engaging and Educating the Community: World TB Day awareness
Compiled by Shrivani Padayachee and Suraksha Chirunt THINKers from the Clinical Trial Unit (CTU) in Hillcrest, South Africa, have been visiting and building relationships with Department of Health facilities as part of the TB ALLIANCE NC-009 trial-related activities. The team was therefore invited to attend two World TB Day events in March, where they were given the opportunity to speak about clinical research and the NC009 trial – as the [...]
A Crucial Step for the TB Alliance NC-009 Study
By Gcina Nhleko THINK’s Strategic Partnerships and Community Health Systems Strengthening department recently convened a meeting attended by members representing the leadership of various community groups – Traditional, Religious, Civil Society – and the Department of Health. The meeting's purpose was to harness community relations and to give a broader outline of the TB Alliance NC-OO9 study and trials imperatives THINK is currently conducting. NC-009 is a pan-Phase 2 [...]
Reflections: World TB Day Event in Denmark
World Tuberculosis (TB) Day, observed annually on March 24th, holds significant importance in the global health calendar, serving as a vital opportunity to raise public awareness about tuberculosis, a potentially deadly infectious disease that primarily affects the lungs. At the “Unpacking Tuberculosis: A Global Issue” event, THINK Denmark brought together influential voices to discuss tackling TB and its cross-cutting issues. Our esteemed panel, featuring experts Rikke Nagell from AIDS-Foundation, Dr. [...]
Finance Induction a Resounding Success
The recent and very successful Finance Induction, at the THINK HQ in Hillcrest, was an opportunity for new THINKers from various districts to meet with the rest of their colleagues. The purpose of the induction was to explain THINK’s processes, policies, and systems, and to make the recruits feel part of the team – and left with a feeling of knowing that they can reach out at any time. “We [...]
THINK: Tackling Public Health Issues
Source: THINK: Tackling Public Health Issues - Africa Outlook MagazineTACKLING PUBLIC HEALTH ISSUESAccording to the World Health Organisation (WHO), tuberculosis (TB) remains the leading cause of death amongst people living with HIV across the world, with the two illnesses being intrinsically linked and in need of vital support.It is from this critical need that THINK was established by Dr Kristina Wallengren as a non-profit company in 2013, with the founding [...]
THINK Accelerate Tuberculosis Elimination and Program Resilience Launch
In an ongoing effort to lessen and eliminate tuberculosis (TB) burden in South Africa, the U.S. Agency for International Development (USAID) has awarded THINK (TB and HIV Investigative Network) funding to roll out the Tuberculosis Elimination and Program Resilience Activity (Accelerate 2), which will run until 2028. ACCELERATE is the flagship USAID/SA TB project, and USAID is the project donor that provides essential funding and support for the execution and [...]
THINK South Africa CEO to partake in the United States: Mandela Washington Fellowship Programme – 2024
Mr Trevor Mvundura, Country CEO at THINK (Tuberculosis & HIV Investigative Network), clinched an illustrious opportunity when he was selected for The Mandela Washington Fellowship for Young African Leaders. This incredibly inspiring program is part of the U.S. Government's Young African Leaders Initiative (YALI). The programme is designed to empower young leaders between their early 20s and mid-30s who have already demonstrated exceptional leadership potential within their communities, organisations, and [...]
Focus on Strategy, Culture and Values
The recent THINK South Africa Roadshow got traction when Trevor Mvundura, our Country CEO, conducted a series of activities – kicking off at the Head Office in Hillcrest on March 1, and continuing throughout the country at the Mangaung office in Bloemfontein, the Fezile Dabi office in Sasolburg, the Centurion office between Pretoria and Midrand, the Vhembe office in Louis Trichardt, and finally the DOH office in Sekhukhune. [...]
News from THINK South Africa’s Clinical Trial Unit
By Dr Munira Khan THINK South Africa's clinical trial unit in Hillcrest is excited to share updates on progress made for the TB ALLIANCE NC009 trial, as well as more info about the ChilPref Ext study The TB ALLIANCE NC009 trial is currently being conducted in five countries and aims to determine the safety of an investigational product in patients with bacteriologically confirmed drug-sensitive TB. One of the potential [...]
Tales of Growth, Impact and Commitment
Meet an inspiring THINKer who lives our values entirely and truthfully – both at work and at home Born and raised in Pietermaritzburg, love and kindness were the cornerstones of Noluthando Gwala’s upbringing, shaping the way she lives her life. Now, as a mother of two wonderful boys, she devotes much of her free time to exploring new recipes with them, watching movies, dancing to the latest TikTok trends, [...]
From Research to Results
By Michaela Higgins Sørensen In the world of non-profit organisations, allocating resources to communications is often left to the last slice of the budget cake. Understandably so, especially when funds are primarily directed towards specialised research, such as revolutionising tuberculosis treatment and changing WHO guidelines. However, at THINK, a research-driven NGO dedicated to healthcare advancement in Southern Africa, we recognise the evolving landscape and the need to elevate our [...]
THINK Pioneers Harnessing AI in Healthcare
By Ziyuan Aria Zhou The Africa Health Conference, hosted by the Harvard T.H. Chan School of Public Health, serves as a platform for discussing and disseminating the transformative initiatives shaping the healthcare landscape across the African continent. Under the theme ‘Mapping Changemakers Transforming Health in Africa’ this year, the conference explored a range of critical themes that capture the complexities of Africa’s healthcare challenges and triumphs. It aimed to highlight [...]
A Journey to Better Health
By Allison Naidoo On February 26th, THINK South Africa collaborated with the National Bioproducts Institute (NBI) for an awareness drive during the NBI Wellness Walkabout, highlighting our shared mission for a healthier future. In the heart of Paradise Valley, the NBI stands as a beacon of hope for South African patients. For more than three decades, NBI has been a cornerstone in the production of essential plasma-derived products, marking a [...]
THINK Commemorates World Tuberculosis (TB) Day
World Tuberculosis (TB) Day, observed annually on March 24, serves as a crucial platform to raise awareness about the global TB epidemic and its profound health, social, and economic impacts. According to World Health Organisation (WHO) data, South Africa ranks among the top five countries worldwide with the highest burden of TB, with over 500 cases per 100,000 population. THINK South Africa, is a local non-profit organisation dedicated to advancing [...]
THINK at the Forefront of World TB Day Commemorations
THINK, a health impact and research organisation are at the forefront of World TB Day initiatives to improve the quality of life for people affected by TB in South Africa and around the world. THINK is part of the ongoing planning meetings led by the office of the Premier in KwaZulu-Natal. World TB Day is a global commemoration held on 24th March of each year and is aimed at building [...]
Welcome, young THINKers!
Let’s meet our new interns in Denmark, and our new students in South Africa! But first, we welcome Michaela – who after a 3-month internship is now onboard with us as THINK Denmark’s Communications Officer. Michaela Higgins Sørensen Communications Officer, Denmark Hi everyone! I'm Michaela, a 27-year-old Danish South African who grew up in Mozambique, but am currently based in Copenhagen. I completed my master’s degree in June 2021, [...]
Strengthening the Fight Against Breast Cancer
Ladies; prioritise your health! Empower yourself with knowledge and regular check-ups to ensure early detection Dr Susan Ford, research doctor at our Clinical Research Unit, has underscored the importance of women's health – a topic that deeply resonates with her. With women often serving as primary caregivers for family members, they sometimes overlook their own health. Susan stresses the value of women's health, particularly in routine checks to detect [...]
TB LON Success Stories
Let's take a look at some of the amazing work we have done!
Innovation and Empathy in Equal Measure
Get to know THINKer Fanelesibonge Msimango – and her wonderful interpretation of THINK culture and values! Fanele joined THINK in February this year as a Data Clerk on the ADAPT project. When the ADAPT project concluded in April, she applied for her current role as a Linkage Coordinator. “In this capacity, I collaborate closely with Linkage Officers to oversee the management of linkage activities. My responsibilities include coordinating the efforts [...]
Advancing HIV Prevention and Protection
In the first part of this year, THINK broadened the scope of the Clinical Trial Unit to include a Male Medical Circumcision (MMC) program. This single intervention reduces the risk of heterosexual transmission of HIV from women to men by about 60%. Further, it reduces the risk of sexually transmitted infections, penile cancer in men, and cervical cancer in female partners of circumcised men. The successful rollout of the [...]
SA has one of the highest TB burdens in the world. Now a researcher is eyeing AI as a new weapon
South Africa is among the top five countries with the highest burden of TB. However, the government recently announced it would be slashing its budget for TB research grants. Now, a researcher plans to use AI to analyse TB data. Machine learning and artificial intelligence (AI) may become a key weapon in fighting South Africa's tuberculosis scourge – which sees as many as 300 000 new infections and more than [...]
Health NGO plans AI training hub in South Africa
Programme will target African health sector workers looking to improve efficiency and outcomes A South African NGO plans to set up a hub in Durban where people working in public health throughout Africa can come to learn how to use AI chatbots in their work. THNK, a non-profit company founded in 2013 to help people affected by TB and HIV, says it hopes to have the hub up and running [...]
Improving Healthcare Access: From Mobile Clinics to TB Literacy
Allison Naidoo takes us on a short journey through our districts, bringing you news of THINK’s impact across the South African province of KwaZulu-Natal. In healthcare's evolving landscape, THINK has been a beacon of hope, making impactful strides across districts. Our journey begins in the uMgungundlovu district, where we've been reshaping healthcare accessibility. September 6 was a significant day for the THINK uMgungundlovu team, who arrived at the Dambuza [...]
The Union Conference: Paris, here we come!
We chat to THINK’s Chief Science Officer, Dr Suzanne Staples, about the upcoming Union World Conference on Lung Health in Paris, and find out more about its importance – both globally and for THINK. The Union World Conference on Lung Health is an annual event organised by the International Union Against Tuberculosis and Lung Disease (The Union). This event has taken place every year for the last 53 years, [...]
From Rural Roots to Global Impact: Meet Siyabonga Myeni
Join us in this insightful Q&A with THINK’s new Business Development Coordinator, where we delve into his vision for THINK's future and innovative strategies for securing partnerships and funding. Siya was born in a rural area called kwa-Hlomendlini (Mandeni), about 100km north of Durban, and raised by his grandmother. This is where he grew up and completed his primary and high school learning, before moving to Johannesburg to study further [...]
Empowering NGOs for Impact: AI Training & Adoption
As promised in last month’s newsletter, here’s Bekani Nsibanyoni’s take on the importance of Artificial Intelligence within the NGO space. Artificial Intelligence is rapidly transforming industries worldwide, and the NGO sector is no exception. The integration of AI into the workings of NGOs can have a profound impact on their ability to deliver services, streamline operations, and address complex societal challenges. To harness the full potential of AI, training is [...]
The Power of Introverts in The Workplace: Kirsty’s Journey
Our Head of Finance & Operations, Kirsty Woolley, uses her own personal journey to explain why there is a big need for introverts in the workplace. From the age of 18 I worked in a bank. It upset me to learn that my colleagues initially perceived me as cold, aloof, a snob and a non-team player. It was not much comfort when, further down the line, these same colleagues would [...]
Meet Camilla Lund, THINK’s new Executive Co-Pilot
Our global administration offices in Copenhagen recently welcomed a dynamic, young humanitarian to the team. Let’s get to know Camilla a bit better! Growing up in Denmark, Camilla moved to France, with her family, when she was 15. Here she attended high school and got her International Baccalaureate. “In Lyon my keen interest in art grew into including street art and graffiti, and my passion for dance was a [...]
The future of a Digital Discovery Hub at THINK
Get up, close and personal with our Senior IT Officer, Bekani Samuel Nsibanyoni! Find out why he places such high importance on IT proficiency, and learn more about his vision of creating an IT Training Development Centre. Q: What can you tell us about the Digital Discovery Hub? A: Today THINK relies heavily on computerised technology to efficiently complete various amounts of tasks. As part of our mission to create [...]
Success Stories from THINK’s uThukela district
SUCCESS STORY 1A 20-year-old male came to Ladysmith’s Steadville clinic on March 21 this year, presenting with loss of appetite, loss of energy, loss of weight, coughing and vomiting blood. Signs and symptoms of TB was noted. Sputum for GXP taken, and the result was positive with Rifampicin Resistance – on March 24. He was referred to Ladysmith Hospital for treatment, and subsequently to Estcourt for DR-TB initiation.Tracing by the [...]
Go, THINK uMkhanyakude!
The team at our uMkhanyakude district office has received a Certificate of Appreciation from the Provincial Office for reaching the target TB success rate.A celebration at the Provincial TB Workshop recently took place, where uMkhanyakude was recognised for doing an excellent job in managing cases of both Drug-Sensitive (DS) and Drug-Resistant (DR) TB.For the last three years, uMkhanyakude has shown great dedication to taking care of TB patients. They achieved [...]
Empowering Communities and Advancing Healthcare
The uMgungundlovu district, a vital hub serving 10% of the provincial population, is a diverse district where challenges overpower opportunities – as the district addresses socio-economic issues like informal settlements and the existing vulnerable key population demographic. With seven municipalities under its umbrella – uMshwathi, Umgeni, Mpofana, Impendle, Msunduzi, UMkhambathini, and Richmond – the district strives to collate a collective response to healthcare needs. There are currently 28 facilities [...]
Greetings from THINK International
We're thrilled to bring you the latest happenings at our new home in Copenhagen! We're now sharing an open office space with our partners at Dalberg Media. A leading social impact advisory group that brings together strategy consulting, design thinking, big data analytics, research, and implementation to address complex social and environmental challenges, Dalberg is a dynamic organisation you should definitely get to know. In our lively co-working environment, we're [...]
Trevor’s Take on THINK Culture
We all know and love the wonderful THINK culture – a vital part of every THINKers well-being and motivation to make a difference daily. Although most of us have individual takes on how we define this unique culture, at the end of the day it all boils down to aligning with our core values. Let’s hear what our inspiring leader, Trevor Mvundura, has to say in this fun Q&A [...]
What’s next for the Hillcrest Clinical Trial Unit?
The two new clinical trials that THINK is currently preparing for are within the fields of HIV prevention in high-risk groups, and individuals diagnosed with drug sensitive TB. The HIV prevention trial is sponsored by GILEAD Inc and offers pre-exposure prophylaxis to individuals at high risk of contracting HIV. The trial is being conducted in a number of countries around the world – including Argentina, Brazil, Puerto Rico, Thailand, United [...]
Applying Artificial Intelligence in Public Health
Hot off the press! If you caught our recent announcement, you know that THINK has secured a grant from the Bill & Melinda Gates Foundation. We're ecstatic to share that we were one of just 50 winners among a staggering 1 300 applications globally, all responding to the Grand Challenges on the Equitable use of AI. Leading the charge on this cutting-edge project, titled "Unlocking the Power of Data," are [...]
Celebrating a Decade of Impactful Healthcare: Reflections with Dr. Suzanne Staples
As we mark THINK's 10th year of impactful work, we celebrate the dedication and expertise of our team of over 500 researchers and healthcare professionals who have provided care for over 0.5 million individuals in KwaZulu-Natal. Through our pioneering clinical research, we have influenced treatment guidelines worldwide and elevated the quality of care in South Africa and beyond. In the spirit of reflection, Dr. Suzanne Staples, our esteemed Chief Strategy [...]
Exciting new partnership: THINK and SASUF collaboration
We are thrilled to announce our partnership with the South Africa-Sweden University Forum (SASUF). SASUF is a collaboration between Swedish and South African universities with the aim of increasing collaboration between the two countries. As part of this partnership, THINK will be hosting a satellite event titled Translating Research into Action on 27-28 March 2023 – during the SASUF Research and Innovation week. This event is a great opportunity for [...]
THINK is venturing into the Metaverse with the launch of our first NFT fundraising project
Feb. 07, 2023 – THINK, with the support of Virtuall, has launched their our very first limited edition NFT (non-fungible token) wearable and ventured into Metaverse where crypto fundraising and virtual engagement with donors is rapidly becoming the norm. The launch of the NFT will enable THINK to adapt to a fast-changing fundraising environment where it is essential to be able to accept crypto donations and engage with a [...]
TB-PRACTECAL: THINK contributing to improve health, shorter treatment, quality of life for patients world-wide!
Findings that prompted WHO to update global DR-TB treatment guidelines now published in the New England Journal of Medicine, show that a much shorter treatment regimen for drug-resistant TB is safer and cured almost 90 percent of patients London, 21 December 2022—A new all-oral, six-month treatment regimen is safer and more effective at treating multidrug-resistant tuberculosis (MDR-TB) than the current options for people with drug-resistant TB (DR-TB), according to the [...]
Three THINKers to present their research at The Union 2022
The Union World Conference on Lung Health 2022 starts tomorrow when researchers, funders and stakeholders will gather virtually until the end of the week to share, discuss and strategize. The theme for this year is "Combating Pandemics: Today and Tomorrow" with the tagline of: "We must work together towards the elimination of all lung health pandemics and this can only be achieved if we address the issues of equity and [...]
In-depth: Use of urine test for TB increasing
Dr Lynette Duckworth, technical TB lead for THINK While tuberculosis (TB) is the top killer of people living with HIV, TB is also harder to diagnose in people living with HIV than in people who are not. What is more, TB is particularly difficult to diagnose in people living with HIV who have compromised immune systems. Imagine, for example, someone living with HIV is very sick and lying [...]
When a Giver, Receives: Donation from Brits Nonwoven
We are thankful to Brits Nonwoven for the donation of D15 masks to THINK: 3442 x Large for Men - Elastic Band Masks, 2481 x Large-Toggle Masks, 8381 x Medium for kids/woman - Elastic Band Masks, 4990 x Medium-Toggle Masks. Thank you so much for your great generosity! Through the Brits Nonwoven donation, we will be able to provide masks for our staff and patients based at our various clinics [...]
The Feasibility and Acceptability of Video Observed Therapy in the Practical Setting of a TB Clinical Trial
7th SA TB Conference 2022 Oral Presentation Track 3: Implementation/Health systems Authors: Siyabonga Myeni, Munira Khan, Suzanne Staples BackgroundVideo Observed Therapy (VOT) is an innovative digital treatment support technology that employs live or recorded video monitoring dosing via a smartphone, tablet or computer. Objectives Among VOT implementors and MDR-TB patients on a TB clinical trial in KwaZulu-Natal, South Africa: To measure acceptability and feasibility of VOT, To identify barriers and [...]
Tuberculosis case yield from LF-LAM: Experience from four districts in KwaZulu-Natal, South Africa
7th SA TB Conference 2022 Poster Presentation Track 3: Implementation/Health systems Authors: Lynette Duckworth; Jayandry Tasha Govender Background Identifying missing TB cases in HIV-positive clients is an ongoing challenge. As a simple point-of-care test, LF-LAM can be performed in 25 minutes using urine, a sample that is readily available. Positive results can be actioned immediately allowing rapid linkage to care and reduction in mortality for HIV/TB-coinfected patients. Challenges of TB-HIV [...]
A qualitative exploration of the effects of psychological well-being and mental health on DR-TB treatment outcomes
7th SA TB Conference 2022 Poster Presentation Track 4: Social and community aspects of TB Authors: Nonhlanhla Ndondo; Dr Suzanne Staples Background Increasingly, researchers are recognizing the detrimental impact of mental ill-health on patients with chronic conditions and opportunistic infections. There is a link between poor mental well-being and treatment non-compliance among chronic illness and HIV patients. South Africa has a high burden of HIV and drug-resistant tuberculosis (DR-TB) [...]
A systematic approach to ascertain linkage to care for DR-TB patients in Eastern Cape
7th SA TB Conference 2022 Poster Presentation Track 3: Implementation/Health systems Authors: Marcel Kitenge1,2, Ruvimbo Chingonzoh3,4, Abraham L.Malaza1, Mcedisi J. Madlavu3, Riyadh Manesen1 1THINK TB & HIV Investigative Network, Hillcrest, KwaZulu- Natal, South Africa. 2Division of Epidemiology and Biostatistics, Department of Global Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa. 3Division of Public Health Surveillance and Response, National Institute for Communicable Disease, National Laboratory Services, [...]
Wheelchair donation makes a difference in the life of a little boy
THINK through the support and donation from the Hillcrest AIDS Centre Trust, we were able to make an incredible difference into a young boy’s and entire families life with a donation of a much needed wheelchair. When one heard the mother of the boy say in a very emotional and soft voice; “Ngiyabonga kakhulu THINK, uNkulunkulu anibusise.” Which can be direct translated to, “Thank you so much THINK, may God [...]
THINK’s new Non-Executive Director
Meet THINK’s new Non-Executive Director, Debbie Gebhardt; an energetic, unbelievably creative and natural leader. Debbie is a veteran Marketing professional with over 25 years of experience, whose career is what every marketing practitioner dreams of; she is a living legend in the creative and marketing space.At THINK, we believe in making a difference in the world with passion and dedication. Our holistic understanding of TB and HIV is the way we [...]
USAID TB LON Annual Program Report 2020
Download report ACRONYMS AND ABBREVIATIONS page 4 EXECUTIVE SUMMARY page 5 PROJECT IMPLEMENTATION BY WORKPLAN OBJECTIVES page 12 GAP 3 and 4) page 22 STAKEHOLDER PARTICIPATION AND INVOLVEMENT page 23 LESSONS LEARNED page 24 CHALLENGES page 25 MANAGEMENT AND ADMINISTRATIVE DUTIES page 26 PROSPECTS FOR THE NEXT YEARS PERFORMANCE page 28 OUTLINE OF THE NEXT STEPS FOR THE NEXT REPORTING PERIOD page 29 ANNEX A: ANNUAL PMP INDICATORS [...]
USAID TB LON Annual Program Report 2021
Download report ACRONYMS AND ABBREVIATIONS page 4 EXECUTIVE SUMMARY page 6 INTRODUCTION page 15 IMPACT OF COVID-19 page 20 RECOVERY PLAN page 26 PROJECT MOBILISATION AS PER WORKPLAN OBJECTIVES page 30 MITIGATION PLANS page 81 STAKEHOLDER MANAGEMENT page 82 RISK ASSESSMENT page 82 STAFF UPDATES page 82 FINANCIAL REPORT page 83 PLANS FOR THE FY22 page 87 SUB RECIPIENT page 89 SUCCESS STORIES / BEST PRACTICE page 90 [...]
THINK’s Winner at the 7th SA TB Conference
Congratulations to Nonhlanhla (Noni) Madondo for winning in the Poster Presentations under Track 4 at the 7th SA TB Conference, for her incredible presentation on ‘Qualitative exploration of the effects of psychological well-being and mental health on DR-TB treatment outcomes in KwaZulu-Natal’. “The SA-TB conference was truly a transformational experience. The energy was electric and it was inspiring to be around people with similar interests who have done amazing work [...]
Pharmacist making a difference at THINK
6 Sep 2022 By Anita Jacobs, pharmacist at THINK I became a pharmacist as I was very interested in caring for human health. The ability to understand health at a much deeper level, translating it to my patients and then witnessing them healthier and recovered drives my passion. Pharmacy is a well-rounded career which involves not only patient care but can incorporate science, innovation, research, technology as well as [...]
UK intern learns about the research THINK does
“Interning at THINK was an amazing opportunity to immerse myself in a South African NGO and learn about the research. Everyone here is passionate about their work, whether it be medical research or finance, and truly are an inspiration. From an outside perspective, the people at THINK are ambitious, hard-working, and want to make a real difference in South African healthcare. Investigating the TB trials has been very interesting, [...]
Programmatic Introduction of the BPaL Regimen: A Practical Implementation Guide
Download Guideline Published: November 2022 Authors: Staples S, Khan M. Howell, P; Juneja, S. Gupta, A In 2021, Dr Suzanne Staples and Dr Munira Khan co-authored a practical implementation guide for use in the programmatic introduction of the BPaL regimen, with key contributions from Dr Pauline Howell (WITS Health Consortium), Sandeep Juneja and Aastha Gupta (TB Alliance) amongst others. This regimen, consisting of Bedaquiline, Pretomanid and Linezolid, [...]
Launch of our Mobile X-ray Units
THINK with the support of @USAID and @kznhealth, launched a brand new fleet of Mobile X-ray vans during the World TB Day event in Howick, Mpophomeni in March. These vans are intended to complement TB screening initiatives among key populations in uThukela, Amajuba, uMgungundlovu and uMkhanyakude districts. Each van is staffed with a radiographer to take X-rays and an enrolled nurse to assess the results and the patient’s overall [...]
Positive signs for new TB testing strategy
Under a new tuberculosis (TB) diagnosis strategy, people considered to be at high risk of TB are offered molecular TB tests, even if they do not have any symptoms. A landmark study in 2020 showed that such a strategy can help diagnose more people more quickly. Now, early indications are that it also works in the real world and South Africa’s lab service says they can cope with the increased [...]
June is National Men’s Health Month!
This month is all about encouraging the men and boys in your life (including you, men out there!) to take care of their bodies by eating right, exercising, and working to prevent disease. The official symbol for the month is a blue ribbon and the purpose of Men’s Health Month is to heighten the awareness of preventable health problems and encourage early detection and treatment of diseases including TB, HIV/AIDS, [...]
THINK proudly contributed to the clinical trials of Bedaquiline, Pretomanid and Delamanid
By Dr Suzanne Staples, Chief Strategy Officer at THINK May 2022 marks such a proud and exciting moment in Drug-Resistant TB care, one that THINK has been closely involved with for many years and right from the start. My personal pride stems from the fact that THINK, and the clinical team has contributed so much to this historic moment through hard work and dedication together with our sponsors and [...]
Pragmatic Clinical Trial for a more Effective Concise and Less toxic MDR-TB treatment regimen(s) (TB-PRACTECAL)
Author: Dr Ronelle Moodliar THINK has proudly participated in the MSF sponsored TB-PRACTECAL clinical research trial since 2017, a phase II/III clinical trial sponsored by Médecins Sans Frontières/Doctors Without Borders (MSF), that tested a six-month regimen of bedaquiline, pretomanid, linezolid and moxifloxacin (BPaLM), amongst 2 others, against the locally accepted standard of care. At the time of the interim analysis 242 patients had been enrolled in seven trial sites across [...]
Promising early signs from mobile X-ray TB screening pilots
One of the most intriguing findings from South Africa’s first National Tuberculosis Prevalence Survey was that out of 234 people found to have TB, 58% had abnormal chest X-rays without experiencing any TB symptoms. Not surprisingly, the short report in which the findings were made public recommended the expanded use of X-ray technology for TB screening, something the World Health Organization (WHO) has also recently recommended.In South Africa the first [...]
SAGE Success story: THINK works smarter to expand its impact
Published Article by SAGE Download Article THINK TB & HIV Investigative Network is a non-profit organisation that conducts world-renowned clinical research in vaccine development, diagnostic tools, and treatment guidelines for TB and HIV. It improves the quality of life of people affected by these diseases through training, capacity building, and engaging with local communities and stakeholders to support and improve health. Since its establishment in [...]
Interactive booklet and pillboxes improve DR-TB treatment adherence
The treatment of Drug- Resistant TB (DR-TB) treatment has rapidly evolved over the last five years with the first new oral DR-TB drug, Bedaquiline, being introduced into the NDOH DR-TB programme in 2017. Following the successful introduction of Bedaquiline into a nine-month all-oral regimen, all treatments for DR-TB in South Africa were transitioned into injection (Kanamycin)- free regimens in 2018. Despite these advances, the treatment regimens for DR-TB remain complex, [...]
Outreach teams are trained to make a difference in their communities
Building the capacity of community outreach teams is one of the priorities of South Africa’s National TB Program (NTP) to improve contact tracing, screening and linkage to TB Preventative Therapy (TPT). Outreach teams consist of community healthcare workers who act as liaisons between communities and their nearest health care facility. At the beginning of 2021, the uMkhanyakude district Department of Health (DoH) requested training on COVID-19, TB and HIV for [...]
USAID TB LON-SAFT impact at East Boom CHC appreciated
During June, the TB/Integrated Services Team Lead for USAID Southern Africa, Ms Cindy Dlamini, visited the East Boom Community Health Centre (CHC) in uMgungundlovu Health District. The visit was facilitated by the USAID TB LON-SAFT Programme, implemented by THINK and the facility management team from the Department of Health. The aim of the visit was for Ms Dlamini to review the impact of the Direct Service Delivery (DSD) support that [...]
Data verification and clean up exercises help improve quality of TB data in eThekwini health facilities
As part of Operation Phuthuma, a 10 Point Plan for Acceleration initiated by the Department of Health (DoH) to improve health service delivery in the country, the eThekwini District DoH embarked on monthly HIV & AIDS, STI and TB (HAST) Programme data clean-up exercises. During February and March 2021, the USAID TB LON-SAFT team collaborated with the district TB Prevention and Control Programme to conduct data verification exercises in health [...]
Nurses share stories from the COVID-19 pandemic for International Nurses Day
On the 12th May 2021, International Nurses’ Day was celebrated and commemorated after a year marked by unknowns, fears, and heavy workloads for most nurses due to the COVID-19 pandemic. Despite this, nurses across the world have faced these challenges and shown innovation and selfless care to millions of patients at health care facilities and at home. The theme of the campaign was “A Voice to Lead – A vision [...]
TB awareness raising as the “clock is ticking” on World TB Day
To commemorate World TB Day on the 24th March 2021, teams from the USAID TB LON-SAFT Programme implemented by THINK, organized various events in March and April. The World TB Day theme for this year was “The Clock is Ticking” conveying a reminder that the world is running out of time to act on the commitments made by global leaders to end TB by 2030. USAID TB LON-SAFT teams in [...]
The USAID TB LON-SAFT Programme implemented by THINK
The USAID TB LON-SAFT Programme was initially awarded to the Tuberculosis and HIV Investigative Network (THINK) to implement in the uMgungundlovu district of KwaZulu-Natal province from 1 October 2019 to 30 September 2020. The aim was to strengthen the drug-resistant tuberculosis (DR-TB) service delivery platform in the district. An extension of this award followed to include drug-susceptible TB (DS-TB) as well for a period from 01 October 2020 until 30 [...]
THINK screens first patients for TB-CHAMP trial assessing levofloxacin as a preventive therapy for DR-TB
Young children and HIV-positive individuals are at high risk of developing tuberculosis (TB) disease following exposure and infection to the Mycobacterium tuberculosis (M. tb) bacteria. In the absence of appropriate preventive therapy, M.tb-infected children under the age of five have a 50% risk of developing TB. More than 90% of children that are exposed to M.tb and who progress to disease, will do so within 12 months while the majority [...]
USG Consul General visits KwaMsane clinic in uMkhanyakude
During the month of June, the USG Consul General (represented by Anne Linnee, Elizabeth Orlando and Baphiwe Nxumalo, the liaison for PEPFAR in the province) and USAID South Africa (represented by Kevin Sturr, the Deputy Mission Director and Phyllis Pholoholo, a project management specialist in TB/HIV clinical care) were introduced to the USAID TB LON-SAFT team in Hlabisa, a subdistrict of uMkhanyakude. The introductory visit started at the Richard’s Bay [...]
Homeless Shelter in Durban residents screen and test for TB
In June 2021, the USAID TB LON-SAFT Programme implemented by THINK conducted a TB Screening Outreach campaign at the Block A.K Homeless Shelter in Durban in collaboration with the eThekwini Municipality, Beatrice Street Primary Health Care (PHC) facility and Stop TB Partnership. The campaign was initiated by the THINK Programme team after learning about a resident from the shelter who was diagnosed and initiated on treatment at the Beatrice PHC [...]
Bedaquiline for multidrug-resistant TB in paediatric patients
THINK’s first paediatric study, sponsored by Janssen Pharmaceuticals, started in May 2015 headed by Dr Ronelle Moodliar at the King Dinuzulu clinical trial site. The study was supported by Seshni Moorgas as the trial coordinator together with Nokuthula Ngcobo and Lungile Phakatias the research nurses. The study contributed towards more than 50% of the total recruited patients globally for cohorts 1 and 2 (>5 to <18 years) and is [...]
Bonginkosi’s Story – THINK’s 240th patient in the MSF clinical trial study
"When I told my wife that I was going to be hospitalized for a long time, she couldn't stop crying." Bonginkosi Emmanuel Mkhize is a 32-year-old refrigerator mechanic based in Durban, South Africa. He is the 240th patient to participate in the MSF study. The aim of this research: to find a new cure for resistant tuberculosis. Tuberculosis Durban is the largest city in the KwaZulu-Natal province, on the east [...]
Health system determinants of tuberculosis mortality in South Africa: a causal loop model
Authors: Muhammad Osman, Aaron S Karat, Munira Khan, Sue-Ann Meehan, Arne von Delft, Zameer Brey, Salome Charalambous, Anneke C Hesseling, Pren Naidoo & Marian Loveday Journal: BMC Health Services Research 21, Article number: 388 (2021) ABSTRACT Background: Tuberculosis (TB) is a major public health concern in South Africa and TB-related mortality remains unacceptably high. Numerous clinical studies have examined the direct causes of TB-related mortality, but its wider, systemic [...]
Improving the quality of TB data in eThekwini health facilities
As part of Operation Phuthuma, a 10 Point Plan for Acceleration initiated by the Department of Health (DoH) to improve health service delivery in the country, the eThekwini District DoH embarked on monthly HIV & AIDS, STI and TB (HAST) Programme data clean-up exercises. During February and March 2021, the USAID TB LON-SAFT team collaborated with the district TB Prevention and Control Programme to conduct data verification exercises in health [...]
A narrative systematic review of tobacco cessation interventions in Sub-Saharan Africa
Published: 29 May 2020Authors: Nasheeta Peer1,2 , Ashika Naicker3 , Munira Khan4 and Andre-Pascal Kengne1,2Journal: SAGE Open Medicine Volume 8: 1–12ABSTRACTAim: In the face of increasing tobacco consumption in Sub-Saharan Africa, it is crucial to not only curb the uptake of tobacco, but to ensure that tobacco users quit. Considering the minimal attention that tobacco cessation interventions receive in Sub- Saharan Africa, this review aims to describe studies that evaluated [...]
Dr Staples is awarded the EDCTP -TDR Clinical Research & Development Fellowship
In September 2017 Doctor Suzanne Staples left for the Netherlands for 1 year as the recipient of the EDCTP -TDR Clinical Research & Development Fellowship. The aim of the fellowship is to build capacity in African researchers through placement at a European Scientific research organisation. Through this placement fellows learn and understand the operation of a scientific clinical research organization, to improve their capacity for conducting future research. To this [...]
What do successful grads think you should study?
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Former student discusses success in the fashion industry
My success is no accident. Etiam consectetur odio erat, quis mattis leo vestibulum non. Fusce ex ligula, tristique quis finibus sed, placerat sed libero. Phasellus convallis, sem ac tristique interdum, purus purus vehicula quam, ut fermentum sem orci in est. Aliquam leo purus, iaculis non condimentum hendrerit, vestibulum quis tortor. Vestibulum quis viverra felis. Vestibulum elementum magna ut diam placerat, in venenatis est egestas. Vivamus at libero auctor, ullamcorper [...]
How do you best prepare for university?
Focus on exam results. Etiam consectetur odio erat, quis mattis leo vestibulum non. Fusce ex ligula, tristique quis finibus sed, placerat sed libero. Phasellus convallis, sem ac tristique interdum, purus purus vehicula quam, ut fermentum sem orci in est. Aliquam leo purus, iaculis non condimentum hendrerit, vestibulum quis tortor. Vestibulum quis viverra felis. Vestibulum elementum magna ut diam placerat, in venenatis est egestas. Vivamus at libero auctor, ullamcorper libero [...]
World TB Day, 2015
On 24 March 1882, Dr. Robert Koch announced that he has discovered the bacterium that causes tuberculosis. It is for this reason that World TB Day is held annually on this day. However, it is not a celebration. We can only celebrate once we have managed to End TB.While in our daily work we are making difference to ensure that this global goal is met by 2035 in our daily [...]
Community-based care vs. centralised hospitalisation for MDRTB patients, KwaZulu-Natal, South Africa
Date: 1 February 2015 Authors: Loveday, M. 1 ; Wallengren, K. 2; Brust, J. 3 ; Roberts, J. 4; Voce, A. 5 ; Margot, B. 6 ; Ngozo, J. 6 ; Master, I. 7 ; Cassell, G. 8 ; Padayatchi, N. 9 ; Publisher: International Union Against Tuberculosis and Lung Disease ABSTRACT: SETTING: KwaZulu-Natal, South Africa, a predominantly rural province with a high burden of tuberculosis (TB), multidrug-resistant TB (MDR-TB) [...]
Drug-Resistant Tuberculosis, KwaZulu-Natal, South Africa, 2001–2007
Date: October, 2011 Authors: Kristina Wallengren, Fabio Scano, Paul Nunn, Bruce Margot, Sandile S.S. Buthelezi, Brian Williams, Alexander Pym, Elisabeth Y. Samuel, Fuad Mirzayev, Wilfred Nkhoma, Lindiwe Mvusi, and Yogan Pillay Publisher: Emerging Infectious Diseases ABSTRACT: In Africa, incidence and prevalence of drug-resistant tuberculosis have been assumed to be low. However, investigation after a 2005 outbreak of extensively drug-resistant tuberculosis in KwaZulu-Natal Province, South Africa, found that the incidence [...]
Harvard Students attend THINK’s course on Translational Medicine
In June, 15 post graduate students from Harvard Medical School missed a flight from the US to attend a course in Translational Medicine hosted by THINK in South Africa. Last minute travel re-arrangements and reshuffling of the week-long course programme enabled the students to still be the first to inaugurate the new THINK Board Room at Florida road in Durban. The course aimed to identify Unmet Medical Needs and Translational [...]
THINK move into new Headquarters
Excited and motivated staff have moved into our new headquarter in 324 Florida road in central Durban. For the first time, the full management can sit together with access to their own boardroom and meeting facilities. An independent research clinic is also located on the premises with state of the art equipment, appropriate infection control, and separate staff working areas.
World TB Day, 2014
In celebration of TB World Day on the 24th of March 2014 THINK arranged a vibrant event at Umkhumbane Secondary School with live performances, inspirational talks, and TB screening. The famous Durban-born baritone singer from London, Njabulo Madlala, inspired crowds of learners with his visit. He talked about “Inspiration” and the ability to achieve anything in life through commitment and hard work. He was backed by his two South African [...]
Comparing early treatment outcomes of MDR-TB in decentralised and centralised settings in KwaZulu-Natal, South Africa
Date: 1 February 2012 Authors: Loveday, M. 1 ; Wallengren, K. 2 ; Voce, A. 3 ; Margot, B. 4 ; Reddy, T.5 ; Master, I. 4 ; Brust, J. 6 ; Chaiyachati, K. 7; Padayatchi, N. 8 ; Publisher: International Union Against Tuberculosis and Lung Disease SETTING: In KwaZulu-Natal, South Africa, a setting endemic for tuberculosis (TB) and the human immunodeficiency virus (HIV), prolonged hospitalisation for the treatment of [...]
Resistance to TB drugs in KwaZulu-Natal causes and prospects for control
Date: 9 July 2011 Authors: Wallengren,1* F. Scano,2 P. Nunn,2 B. Margot,3 S. Buthelezi,3 B. Williams,4 A. Pym,5 E. Y. Samuel,6 F. Mirzayev,2 W. Nkhoma7, L. Mvusi,8 and Y. Pillay8 Abstract: Background: In 2005 there was an outbreak of XDR (extensively drug resistant) TB in Tugela Ferry, which is served by the Church of Scotland Hospital (COSH), in the uMzinyathi District, KwaZulu-Natal, South Africa. An investigation was carried out to [...]
